ELISA RPRD1B Antibody, FITC

Quantity :50µg Clone Number: Aliases:RPRD1B antibody; C20orf77 antibody; CREPT antibody; RegµLation of nuclear pre-mRNA domain-containing protein 1B antibody; Cell cycle-related and expression-elevated protein in tumor antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:Q9NQG5 Immunogen:Recombinant RegµLation of nuclear pre-mRNA domain-containing protein 1B protein (2-172AA) Raised in:Rabbit Reactivity: Tested Applications: Background:Interacts with phosphorylated C-terminal heptapeptide repeat domain (CTD) of the largest RNA polymerase II subunit POLR2A, and participates in dephosphorylation of the CTD. Transcriptional regµLator which enhances expression of CCND1. Promotes binding of RNA polymerase II to the CCDN1 promoter and to the termination region before the poly-A site but decreases its binding after the poly-A site. Prevents RNA polymerase II from reading throµgh the 3\' end termination site and may allow it to be recruited back to the promoter throµgh promotion of the formation of a chromatin loop. Also enhances the transcription of a number of other cell cycle-related genes including CDK2, CDK4, CDK6 and cyclin-E but not CDKN1A, CDKN1B or cyclin-A. Promotes cell proliferation. Clonality:Polyclonal Isotype:IgG Purification Method:>95%, Protein G purified Conjµgate:FITC Buffer:Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:RPRD1B Research Areas:Cell biology