ELISA TNKS2 Antibody, Biotin

Quantity :50µg Clone Number: Aliases:ADP-ribosyltransferase diphtheria toxin-like 6 antibody; ARTD6 antibody; PARP 5b antibody; PARP 5c antibody; PARP-5b antibody; PARP-5c antibody; PARP5B antibody; PARP5C antibody; pART6 antibody; Poly [ADP ribose] polymerase 5B antibody; Poly [ADP-ribose] polymerase 5B antibody; TANK2 antibody; Tankyrase 2 antibody; Tankyrase II antibody; Tankyrase like protein antibody; Tankyrase related protein antibody; Tankyrase TRF1 interacting ankyrin related ADP ribose polymerase 2 antibody; Tankyrase-2 antibody; Tankyrase-like protein antibody; Tankyrase-related protein antibody; TNKL antibody; TNKS 2 antibody; TNKS-2 antibody; TNKS2 antibody; TNKS2_ antibody; TRF1 Interacting Ankyrin Related ADP ribose polymerase 2 antibody; TRF1-interacting ankyrin-related ADP-ribose polymerase 2 antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:Q9H2K2 Immunogen:Recombinant Tankyrase-2 protein (1-246AA) Raised in:Rabbit Reactivity: Tested Applications:ELISA Background:Poly-ADP-ribosyltransferase involved in various processes such as Wnt signaling pathway, telomere length and vesicle trafficking. Acts as an activator of the Wnt signaling pathway by mediating poly-ADP-ribosylation of AXIN1 and AXIN2, 2 key components of the beta-catenin destruction complex: poly-ADP-ribosylated target proteins are recognized by RNF146, which mediates their ubiquitination and subsequent degradation. Also mediates poly-ADP-ribosylation of BLZF1 and CASC3, followed by recruitment of RNF146 and subsequent ubiquitination. Mediates poly-ADP-ribosylation of TERF1, thereby contributing to the regµLation of telomere length. May also regµLate vesicle trafficking and modµLate the subcellµLar distribution of SLC2A4/GLUT4-vesicles. StimµLates 26S proteasome activity. Clonality:Polyclonal Isotype:IgG Purification Method:>95%, Protein G purified Conjµgate:Biotin Buffer:Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:TNKS2 Research Areas:Epigenetics and Nuclear Signaling; Signal transduction