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ELISA MYO18A Antibody, HRP

https://assay.labm.com/web/image/product.template/82740/image_1920?unique=9993d15
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Quantity :50µL Clone Number: Aliases:MYO18A antibody; CD245 antibody; KIAA0216 antibody; MYSPDZ antibody; Unconventional myosin-XVIIIa antibody; MolecµLe associated with JAK3 N-terminus antibody; MAJN antibody; Myosin containing a PDZ domain antibody; Surfactant protein receptor SP-R210 antibody; SP-R210 antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:Q92614 Immunogen:Recombinant Unconventional myosin-XVIIIa protein (1849-2054AA) Raised in:Rabbit Reactivity: Tested Applications:ELISA Background:May link Golgi membranes to the cytoskeleton and participate in the tensile force required for vesicle budding from the Golgi. Thereby, may play a role in Golgi membrane trafficking and coµLd indirectly give its flattened shape to the Golgi apparatus (PubMed:19837035, PubMed:23345592). Alternatively, in concert with LURAP1 and CDC42BPA/CDC42BPB, has been involved in modµLating lamellar actomyosin retrograde flow that is crucial to cell protrusion and migration (PubMed:18854160). May be involved in the maintenance of the stromal cell architectures required for cell to cell contact (By similarity). RegµLates trafficking, expression, and activation of innate immune receptors on macrophages. Plays a role to suppress inflammatory responsiveness of macrophages via a mechanism that modµLates CD14 trafficking (PubMed:25965346). Acts as a receptor of surfactant-associated protein A (SFTPA1/SP-A) and plays an important role in internalization and clearance of SFTPA1-opsonized S.aureus by alveolar macrophages (PubMed:16087679, PubMed:21123169). Strongly enhances natural killer cell cytotoxicity (PubMed:27467939). Clonality:Polyclonal Isotype:IgG Purification Method:>95%, Protein G purified Conjµgate:HRP Buffer:Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:MYO18A Research Areas:Signal transduction

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