ELISA Cobra venom factor Antibody, HRP

Quantity :50µg Clone Number: Aliases:antibody; Cobra venom factor antibody; CVF antibody; CVFk antibody; Complement C3 homolog) [Cleaved into: Cobra venom factor alpha chain; Cobra venom factor gamma chain; Cobra venom factor beta chain] antibody Product Type:Polyclonal Antibody Immunogen Species:Naja kaouthia (Monocled cobra) (Naja siamensis) UniProt ID:Q91132 Immunogen:Recombinant Naja kaouthia Cobra venom factor protein (733-984AA) Raised in:Rabbit Reactivity:Naja kaouthia Tested Applications:ELISA Background:Complement-activating protein in cobra venom. It is a structural and functional analog of complement component C3b, the activated form of C3. It binds factor B (CFB), which is subsequently cleaved by factor D (CFD) to form the bimolecµLar complex CVF/Bb. CVF/Bb is a C3/C5 convertase that cleaves both complement components C3 and C5. Structurally, it resembles the C3b degradation product C3c, which is not able to form a C3/C5 convertase. Unlike C3b/Bb, CVF/Bb is a stable complex and completely resistant to the actions of complement regµLatory factors H (CFH) and I (CFI). Therefore, CVF continuously activates complement resµLting in the depletion of complement activity. Clonality:Polyclonal Isotype:IgG Purification Method:>95%, Protein G purified Conjµgate:HRP Buffer:Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names: Research Areas:Others