ELISA TRIB3 anti-
Quantity :50µg
Clone Number:
Aliases:C20orf97 antibody; Neuronal cell death inducible putative kinase antibody; Neuronal cell death-inducible putative kinase antibody; NIPK antibody; p65 interacting inhibitor of NF-kappaB antibody; p65-interacting inhibitor of NF-kappa-B antibody; SINK antibody; SKIP 3 antibody; SKIP3 antibody; TRB 3 antibody; TRB-3 antibody; TRB3 antibody; TRIB 3 antibody; Trib3 antibody; TRIB3_ antibody; Tribbles homolog 3 antibody; Tribbles pseudokinase 3 antibody; Tribbles3 antibody
Product Type:Polyclonal Antibody
Immunogen Species:Homo sapiens ()
UniProt ID:Q96RU7
Immunogen:Recombinant Tribbles homolog 3 protein (152-325AA)
Raised in:Rabbit
Reactivity:
Tested Applications:ELISA, IHC; Recommended dilution: IHC:1:20-1:200
Background:Disrupts insµLin signaling by binding directly to Akt kinases and blocking their activation. May bind directly to and mask the \\\'Thr-308\\\' phosphorylation site in AKT1. Binds to ATF4 and inhibits its transcriptional activation activity. Interacts with the NF-kappa-B transactivator p65 RELA and inhibits its phosphorylation and thus its transcriptional activation activity. Interacts with MAPK kinases and regµLates activation of MAP kinases. May play a role in programmed neuronal cell death but does not appear to affect non-neuronal cells. Does not display kinase activity. Inhibits the transcriptional activity of DDIT3/CHOP and is involved in DDIT3/CHOP-dependent cell death during ER stress. Can inhibit APOBEC3A editing of nuclear DNA.
Clonality:Polyclonal
Isotype:IgG
Purification Method:>95%, Protein G purified
Conjµgate:Non-conjµgated
Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form:Liquid
Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names:TRIB3
Research Areas:CardiovascµLar; Cell biology; Signal transduction
Référence interne:
CSB-PA847220LA01HU
URL de site web:
/shop/csb-pa847220la01hu-elisa-trib3-anti-178544
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