ELISA QKI anti-

Quantity :50µL Clone Number: Aliases:DKFZp586I0923 antibody; HKQ antibody; Homolog of mouse quaking QKI KH domain RNA binding protein antibody; Hqk antibody; HQK1 antibody; HqkI antibody; OTTHUMP00000017581 antibody; OTTHUMP00000017582 antibody; OTTHUMP00000017583 antibody; Protein quaking antibody; QK antibody; QK1 antibody; QK3 antibody; QKI antibody; QKI_ antibody; QKI1 antibody; Quaking homolog antibody; Quaking homolog KH domain RNA binding antibody; Quaking homolog KH domain RNA binding mouse antibody; Quaking isoform 1 antibody; Quaking protein antibody; RNA binding protein HQK antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:Q96PU8 Immunogen:Recombinant Protein quaking protein (1-341AA) Raised in:Rabbit Reactivity: Tested Applications:ELISA, WB, IHC; Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200 Background:RNA-binding protein that plays a central role in myelinization (PubMed:16641098). Binds to the 5\\\'-NACUAAY-N(1,20)-UAAY-3\\\' RNA core sequence. RegµLates target mRNA stability (PubMed:23630077). In addition, acts by regµLating pre-mRNA splicing, mRNA export and protein translation. Required to protect and promote stability of mRNAs such as MBP and CDKN1B. RegµLator of oligodendrocyte differentiation and maturation in the brain that may play a role in myelin and oligodendrocyte dysfunction in schizophrenia (PubMed:16641098). Participates in mRNA transport by regµLating the nuclear export of MBP mRNA. Also involved in regµLation of mRNA splicing of MAG pre-mRNA. Acts as a translational repressor (By similarity). Clonality:Polyclonal Isotype:IgG Purification Method:Antigen Affinity Purified Conjµgate:Non-conjµgated Buffer:PBS with 0.02% sodium azide, 50% glycerol, pH7.3. Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:QKI Research Areas:Epigenetics and Nuclear Signaling; Neuroscience; Signal transduction