ELISA MRGPRX2 Antibody, FITC
Quantity :50µg
Clone Number:
Aliases:G protein coupled receptor MRGX 2 antibody; G protein coupled receptor MRGX2 antibody; Mas related G protein coupled receptor member X2 antibody; Mas related gene MRGX 2 antibody; Mas related gene MRGX2 antibody; MAS related GPR member X2 antibody; Mas-related G-protein coupled receptor member X antibody; Mas-related G-protein coupled receptor member X2 antibody; MRGPRX 2 antibody; MRGPRX2 antibody; MRGX 2 antibody; MRGX2 antibody; MRGX2_ antibody
Product Type:Polyclonal Antibody
Immunogen Species:Homo sapiens ()
UniProt ID:Q96LB1
Immunogen:Recombinant Mas-related G-protein coupled receptor member X2 protein (286-330AA)
Raised in:Rabbit
Reactivity:
Tested Applications:
Background:Mast cell-specific receptor for basic secretagogues, i.e. cationic amphiphilic drµgs, as well as endo- or exogenous peptides, consisting of a basic head group and a hydrophobic core (PubMed:25517090). Recognizes and binds small molecµLes containing a cyclized tetrahydroisoquinoline (THIQ), such as non-steroidal neuromuscµLar blocking drµgs (NMBDs), including tubocurarine and atracurium. In response to these compounds, mediates pseudo-allergic reactions characterized by histamine release, inflammation and airway contraction. Acts as a receptor for a number of other ligands, including peptides and alkaloids, such as cortistatin-14, proadrenomedµLlin N-terminal peptides PAMP-12 and, at lower extent, PAMP-20, antibacterial protein LL-37, PMX-53 peptide, beta-defensins, and complanadine A.
Clonality:Polyclonal
Isotype:IgG
Purification Method:>95%, Protein G purified
Conjµgate:FITC
Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form:Liquid
Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names:MRGPRX2
Research Areas:Neuroscience; Signal transduction
Référence interne:
CSB-PA839361LC01HU
URL de site web:
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