ELISA SGK3 anti-

Quantity :50µL Clone Number: Aliases:CISK antibody; Cytokine independent survival kinase antibody; DKFZp781N0293 antibody; Serine/threonine protein kinase Sgk3 antibody; Serine/threonine-protein kinase Sgk3 antibody; Serum/glucocorticoid regµLated kinase 3 antibody; Serum/glucocorticoid regµLated kinase family member 3 antibody; Serum/glucocorticoid regµLated kinase like antibody; Serum/glucocorticoid-regµLated kinase 3 antibody; Serum/glucocorticoid-regµLated kinase-like antibody; SGK 2 antibody; SGK 3 antibody; SGK2 antibody; Sgk3 antibody; SGK3_ antibody; SGKL antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:Q96BR1 Immunogen:Recombinant Serine/threonine-protein kinase Sgk3 protein (1-150AA) Raised in:Rabbit Reactivity: Tested Applications:ELISA, IHC; Recommended dilution: IHC:1:20-1:200 Background:Serine/threonine-protein kinase which is involved in the regµLation of a wide variety of ion channels, membrane transporters, cell growth, proliferation, survival and migration. Up-regµLates Na+ channels: SCNN1A/ENAC and SCN5A, K+ channels: KCNA3/KV1.3, KCNE1, KCNQ1 and KCNH2/HERG, epithelial Ca2+ channels: TRPV5 and TRPV6, chloride channel: BSND, creatine transporter: SLC6A8, Na+/dicarboxylate cotransporter: SLC13A2/NADC1, Na+-dependent phosphate cotransporter: SLC34A2/NAPI-2B, amino acid transporters: SLC1A5/ASCT2 and SLC6A19, glutamate transporters: SLC1A3/EAAT1, SLC1A6/EAAT4 and SLC1A7/EAAT5, glutamate receptors: GRIA1/GLUR1 and GRIK2/GLUR6, Na+/H+ exchanger: SLC9A3/NHE3, and the Na+/K+ ATPase. Plays a role in the regµLation of renal tubµLar phosphate transport and bone density. Phosphorylates NEDD4L and GSK3B. Positively regµLates ER transcription activity throµgh phosphorylation of FLII. Negatively regµLates the function of ITCH/AIP4 via its phosphorylation and thereby prevents CXCR4 from being efficiently sorted to lysosomes. Clonality:Polyclonal Isotype:IgG Purification Method:Antigen Affinity Purified Conjµgate:Non-conjµgated Buffer:PBS with 0.02% sodium azide, 50% glycerol, pH7.3. Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:SGK3 Research Areas:Metabolism; Signal transduction