ELISA SPC24 Antibody, Biotin

Quantity :50µg Clone Number: Aliases:FLJ90806 antibody; hSpc24 antibody; Kinetochore protein Spc24 antibody; SPBC24 antibody; spc24 antibody; SPC24 NDC80 kinetochore complex component antibody; SPC24 NDC80 kinetochore complex component homolog antibody; SPC24, NDC80 kinetochore complex component, homolog (S. cerevisiae) antibody; SPC24_ antibody; Spindle pole body component 24 homolog (S. cerevisiae) antibody; Spindle pole body component 24 homolog antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:Q8NBT2 Immunogen:Recombinant Kinetochore protein Spc24 protein (21-97AA) Raised in:Rabbit Reactivity: Tested Applications:ELISA Background:Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity (PubMed:14738735). Required for kinetochore integrity and the organization of stable microtubµLe binding sites in the outer plate of the kinetochore (PubMed:14738735). The NDC80 complex synergistically enhances the affinity of the SKA1 complex for microtubµLes and may allow the NDC80 complex to track depolymerizing microtubµLes (PubMed:23085020). Clonality:Polyclonal Isotype:IgG Purification Method:>95%, Protein G purified Conjµgate:Biotin Buffer:Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:SPC24 Research Areas:Epigenetics and Nuclear Signaling; Cell biology