ELISA SLC5A8 Antibody, FITC

Quantity :50µg Clone Number: Aliases:AIT antibody; Apical iodide transporter antibody; Electrogenic sodium monocarboxylate cotransporter antibody; MGC125354 antibody; SC5A8_ antibody; SLC5A8 antibody; SMCT antibody; SMCT1 antibody; sodium coupled monocarboxylate transporter 1 antibody; Sodium iodide related cotransporter antibody; Sodium iodide-related cotransporter antibody; Sodium-coupled monocarboxylate transporter 1 antibody; solute carrier family 5 iodide transporter member 8 antibody; Solute carrier family 5 member 8 antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:Q8N695 Immunogen:Recombinant Sodium-coupled monocarboxylate transporter 1 protein (540-610AA) Raised in:Rabbit Reactivity: Tested Applications: Background:Acts as an electrogenic sodium (Na(+)) and chloride (Cl-)-dependent sodium-coupled solute transporter, including transport of monocarboxylates (short-chain fatty acids including L-lactate, D-lactate, pyruvate, acetate, propionate, valerate and butyrate), lactate, mocarboxylate drµgs (nicotinate, benzoate, salicylate and 5-aminosalicylate) and ketone bodies (beta-D-hydroxybutyrate, acetoacetate and alpha-ketoisocaproate), with a Na(+):substrate stoichiometry of between 4:1 and 2:1. Catalyzes passive carrier mediated diffusion of iodide. Mediates iodide transport from the thyrocyte into the colloid lumen throµgh the apical membrane. May be responsible for the absorption of D-lactate and monocarboxylate drµgs from the intestinal tract. Acts as a tumor suppressor, suppressing colony formation in colon cancer, prostate cancer and glioma cell lines. May play a critical role in the entry of L-lactate and ketone bodies into neurons by a process driven by an electrochemical Na(+) gradient and hence contribute to the maintenance of the energy status and function of neurons. Clonality:Polyclonal Isotype:IgG Purification Method:>95%, Protein G purified Conjµgate:FITC Buffer:Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:SLC5A8 Research Areas:Neuroscience; Cancer; Cell biology; Metabolism; Signal transduction