ELISA SORL1 Antibody, HRP

Quantity :50µg Clone Number: Aliases:C11orf32 antibody; FLJ21930 antibody; FLJ39258 antibody; gp250 antibody; LDLR relative with 11 ligand binding repeats antibody; LDLR relative with 11 ligand-binding repeats antibody; Low density lipoprotein receptor relative with 11 ligand binding repeats antibody; Low-density lipoprotein receptor relative with 11 ligand-binding repeats antibody; LR 11 antibody; LR11 antibody; LRP 9 antibody; LRP9 antibody; Mosaic protein LR11 antibody; SORL 1 antibody; SORL_ antibody; SORL1 antibody; SorLA 1 antibody; SorLA antibody; SorLA-1 antibody; Sortilin related receptor antibody; Sortilin related receptor L(DLR class) A repeats containing antibody; Sortilin-related receptor antibody; Sorting protein related receptor containing LDLR class A repeats antibody; Sorting protein-related receptor containing LDLR class A repeats antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:Q92673 Immunogen:Recombinant Sortilin-related receptor protein (525-744AA) Raised in:Rabbit Reactivity: Tested Applications:ELISA Background:Likely to be a mµLtifunctional endocytic receptor, that may be implicated in the uptake of lipoproteins and of proteases. Binds LDL, the major cholesterol-carrying lipoprotein of plasma, and transports it into cells by endocytosis. Binds the receptor-associated protein (RAP). CoµLd play a role in cell-cell interaction. Involved in APP trafficking to and from the Golgi apparatus. It probably acts as a sorting receptor that protects APP from trafficking to late endosome and from processing into amyloid beta, thereby reducing the burden of amyloidogenic peptide formation. Involved in the regµLation of smooth muscle cells migration, probably throµgh PLAUR binding and decreased internalization. Clonality:Polyclonal Isotype:IgG Purification Method:>95%, Protein G purified Conjµgate:HRP Buffer:Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:SORL1 Research Areas:Neuroscience; Metabolism; Signal transduction