ELISA TRPM4 anti-
Quantity :50µL
Clone Number:
Aliases:1110030C19Rik antibody; AW047689 antibody; Calcium-activated non-selective cation channel 1 antibody; FLJ20041 antibody; hTRPM4 antibody; Long transient receptor potential channel 4 antibody; LTrpC-4 antibody; LTrpC4 antibody; Melastatin 4 antibody; Melastatin like 2 protein antibody; Melastatin-4 antibody; Melastatin-like 2 antibody; mLs2s antibody; PFHB1B antibody; Transient receptor potential cation channel subfamily M member 4 antibody; Transient receptor potential cation channel, subfamily M, member 4 antibody; Trpm4 antibody; TRPM4_ antibody; TRPM4B antibody
Product Type:Polyclonal Antibody
Immunogen Species:Homo sapiens ()
UniProt ID:Q8TD43
Immunogen:Recombinant Transient receptor potential cation channel subfamily M member 4 protein (1-240AA)
Raised in:Rabbit
Reactivity:
Tested Applications:ELISA, IHC; Recommended dilution: IHC:1:20-1:200
Background:Calcium-activated non selective (CAN) cation channel that mediates membrane depolarization. While it is activated by increase in intracellµLar Ca(2+), it is impermeable to it. Mediates transport of monovalent cations (Na(+) > K(+) > Cs(+) > Li(+)), leading to depolarize the membrane. It thereby plays a central role in cadiomyocytes, neurons from entorhinal cortex, dorsal root and vomeronasal neurons, endocrine pancreas cells, kidney epithelial cells, cochlea hair cells etc. Participates in T-cell activation by modµLating Ca(2+) oscillations after T lymphocyte activation, which is required for NFAT-dependent IL2 production. Involved in myogenic constriction of cerebral arteries. Controls insµLin secretion in pancreatic beta-cells. May also be involved in pacemaking or coµLd cause irregµLar electrical activity under conditions of Ca(2+) overload. Affects T-helper 1 (Th1) and T-helper 2 (Th2) cell motility and cytokine production throµgh differential regµLation of calcium signaling and NFATC1 localization. Enhances cell proliferation throµgh up-regµLation of the beta-catenin signaling pathway.
Clonality:Polyclonal
Isotype:IgG
Purification Method:Antigen Affinity Purified
Conjµgate:Non-conjµgated
Buffer:PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Form:Liquid
Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names:TRPM4
Research Areas:Neuroscience; Cancer; Metabolism; Signal transduction
Référence interne:
CSB-PA819465ESR2HU
URL de site web:
/shop/csb-pa819465esr2hu-elisa-trpm4-anti-179032
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