ELISA SKA3 Antibody, HRP

Quantity :50µg Clone Number: Aliases:C13orf3 antibody; RAMA1 antibody; SKA3 antibody; SKA3_ antibody; Spindle and kinetochore associated complex subunit 3 antibody; Spindle and kinetochore-associated protein 3 antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:Q8IX90 Immunogen:Recombinant Spindle and kinetochore-associated protein 3 protein (101-195AA) Raised in:Rabbit Reactivity: Tested Applications:ELISA Background:Component of the SKA1 complex, a microtubµLe-binding subcomplex of the outer kinetochore that is essential for proper chromosome segregation (PubMed:19289083, PubMed:19360002, PubMed:23085020). The SKA1 complex is a direct component of the kinetochore-microtubµLe interface and directly associates with microtubµLes as oligomeric assemblies (PubMed:19289083, PubMed:19360002). The complex facilitates the processive movement of microspheres along a microtubµLe in a depolymerization-coupled manner (PubMed:19289083). In the complex, it mediates the microtubµLe-stimµLated oligomerization (PubMed:19289083). Affinity for microtubµLes is synergistically enhanced in the presence of the ndc-80 complex and may allow the ndc-80 complex to track depolymerizing microtubµLes (PubMed:23085020). Clonality:Polyclonal Isotype:IgG Purification Method:>95%, Protein G purified Conjµgate:HRP Buffer:Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:SKA3 Research Areas:Cell biology