ELISA WDFY3 Antibody, Biotin

Quantity :50µg Clone Number: Aliases:WDFY3 antibody; KIAA0993 antibody; WD repeat and FYVE domain-containing protein 3 antibody; Autophagy-linked FYVE protein antibody; Alfy antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:Q8IZQ1 Immunogen:Recombinant WD repeat and FYVE domain-containing protein 3 protein (1-100AA) Raised in:Rabbit Reactivity: Tested Applications:ELISA Background:Required for selective autophagy (aggrephagy) but not for autophagic degradation of bµLk cytospol in response to starvation. Involved in the formation and degradation of cytoplasmic polyubiquitin-containing bodies (p62 bodies, ALIS/aggresome-like induced structures). May play a role as adaptor or scaffolding protein by promoting the association of the E3-like ligase ATG12-ATG5-ATG16L and LC3 to ubiquitinated target substrate. The association with GABARAP is required for its recruitment to LC3B-positive p62 bodies sµggesting a role in targeting certain p62 structures for clearance. Involved in midbody ring degradation. Clonality:Polyclonal Isotype:IgG Purification Method:>95%, Protein G purified Conjµgate:Biotin Buffer:Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:WDFY3 Research Areas:CardiovascµLar