ELISA DNAJC10 Antibody, Biotin

Quantity :50µL Clone Number: Aliases:DNAJC10 antibody; ERDJ5 antibody; UNQ495/PRO1012DnaJ homolog subfamily C member 10 antibody; EC 1.8.4.- antibody; Endoplasmic reticµLum DNA J domain-containing protein 5 antibody; ER-resident protein ERdj5 antibody; ERdj5 antibody; Macrothioredoxin antibody; MTHr antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:Q8IXB1 Immunogen:Recombinant DnaJ homolog subfamily C member 10 protein (521-793AA) Raised in:Rabbit Reactivity: Tested Applications:ELISA Background:Endoplasmic reticµLum disµLfide reductase involved both in the correct folding of proteins and degradation of misfolded proteins. Required for efficient folding of proteins in the endoplasmic reticµLum by catalyzing the removal of non-native disµLfide bonds formed during the folding of proteins, such as LDLR. Also involved in endoplasmic reticµLum-associated degradation (ERAD) by reducing incorrect disµLfide bonds in misfolded glycoproteins recognized by EDEM1. Interaction with HSPA5 is required its activity, not for the disµLfide reductase activity, but to facilitate the release of DNAJC10 from its substrate. Promotes apoptotic signaling pathway in response to endoplasmic reticµLum stress. Clonality:Polyclonal Isotype:IgG Purification Method:Antigen Affinity Purified Conjµgate:Biotin Buffer:Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:DNAJC10 Research Areas:Signal transduction