ELISA UBR2 anti-

Quantity :50µg Clone Number: Aliases:UBR2 antibody; C6orf133 antibody; KIAA0349 antibody; E3 ubiquitin-protein ligase UBR2 antibody; EC 2.3.2.27 antibody; N-recognin-2 antibody; RING-type E3 ubiquitin transferase UBR2 antibody; Ubiquitin-protein ligase E3-alpha-2 antibody; Ubiquitin-protein ligase E3-alpha-II antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:Q8IWV8 Immunogen:Recombinant E3 ubiquitin-protein ligase UBR2 protein (101-439AA) Raised in:Rabbit Reactivity:, Mouse Tested Applications:ELISA, WB; Recommended dilution: WB:1:1000-1:5000 Background:E3 ubiquitin-protein ligase which is a component of the N-end rµLe pathway. Recognizes and binds to proteins bearing specific N-terminal residues that are destabilizing according to the N-end rµLe, leading to their ubiquitination and subsequent degradation. Plays a critical role in chromatin inactivation and chromosome-wide transcriptional silencing during meiosis via ubiquitination of histone H2A. Binds leucine and is a negative regµLator of the leucine-mTOR signaling pathway, thereby controlling cell growth. Clonality:Polyclonal Isotype:IgG Purification Method:>95%, Protein G purified Conjµgate:Non-conjµgated Buffer:Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:UBR2 Research Areas:Cell biology