ELISA VPS4B anti-

Quantity :50µL Clone Number: Aliases:vacuolar protein sorting 4 homolog B (S. cerevisiae) Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:O75351 Immunogen:Synthetic peptide of VPS4B Raised in:Rabbit Reactivity: Tested Applications:ELISA, IHC; ELISA:1:1000-1:2000, IHC:1:10-1:50 Background:The protein encoded by this gene is a member of the AAA protein family (ATPases associated with diverse cellµLar activities), and is the homolog of the yeast Vps4 protein. In s, two paralogs of the yeast protein have been identified. The former share a high degree of aa sequence similarity with each other, and also with yeast Vps4 and mouse Skd1 proteins. Mouse Skd1 (suppressor of K+ transport defect 1) has been shown to be a yeast Vps4 ortholog. Functional studies indicate that both paralogs associate with the endosomal compartments, and are involved in intracellµLar protein trafficking, similar to Vps4 protein in yeast. The gene encoding this paralog has been mapped to chromosome 18; the gene for the other resides on chromosome 16. Clonality:Polyclonal Isotype:IgG Purification Method:Antigen affinity purification Conjµgate:Non-conjµgated Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:VPS4B Research Areas:Signal transduction