ELISA VPS36 Antibody, HRP

Quantity :50µL Clone Number: Aliases:C13orf9 antibody; CGI 145 antibody; EAP45 antibody; ELL associated protein of 45 kDa antibody; ELL-associated protein of 45 kDa antibody; ESCRT-II complex subunit VPS36 antibody; Vacuolar protein sorting associated protein 36 antibody; Vacuolar protein-sorting-associated protein 36 antibody; Vps36 antibody; VPS36_ antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:Q86VN1 Immunogen:Peptide sequence from Vacuolar protein-sorting-associated protein 36 protein (87-105AA) Raised in:Rabbit Reactivity: Tested Applications:ELISA Background:Component of the ESCRT-II complex (endosomal sorting complex required for transport II), which is required for mµLtivesicµLar body (MVB) formation and sorting of endosomal cargo proteins into MVBs. The MVB pathway mediates delivery of transmembrane proteins into the lumen of the lysosome for degradation. The ESCRT-II complex is probably involved in the recruitment of the ESCRT-III complex. Its ability to bind ubiquitin probably plays a role in endosomal sorting of ubiquitinated cargo proteins by ESCRT complexes. The ESCRT-II complex may also play a role in transcription regµLation, possibly via its interaction with ELL. Binds phosphoinosides such as PtdIns(3,4,5)P3. Clonality:Polyclonal Isotype:IgG Purification Method:Antigen Affinity Purified Conjµgate:HRP Buffer:Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:VPS36 Research Areas:Cell biology; Signal transduction