ELISA SMAD3 (Ab-425) anti-

Quantity :100µL Clone Number: Aliases:DKFZP586N0721 antibody; DKFZp686J10186 antibody; hMAD 3 antibody; hMAD-3 antibody; hSMAD3 antibody; HSPC193 antibody; HST17436 antibody; JV15 2 antibody; JV15-2 antibody; JV152 antibody; LDS1C antibody; LDS3 antibody; MAD (mothers against decapentaplegic Drosophila) homolog 3 antibody; MAD homolog 3 antibody; Mad homolog JV15 2 antibody; Mad protein homolog antibody; MAD; mothers against decapentaplegic homolog 3 antibody; Mad3 antibody; MADH 3 antibody; MADH3 antibody; MGC60396 antibody; Mothers against decapentaplegic homolog 3 antibody; Mothers against DPP homolog 3 antibody; SMA and MAD related protein 3 antibody; SMAD 3 antibody; SMAD antibody; SMAD family member 3 antibody; SMAD; mothers against DPP homolog 3 antibody; Smad3 antibody; SMAD3_ antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:P84022 Immunogen:Peptide sequence around aa.423~427 (C-S-S-V-S) derived from Smad3. Raised in:Rabbit Reactivity:, Mouse, Rat Tested Applications:ELISA, IHC, IF; IHC:1:50-1:100, IF:1:100-1:200 Background:Smad3 encoded by this gene belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modµLators that mediate mµLtiple signaling pathways. This protein functions as a transcriptional modµLator activated by transforming growth factor-beta and is thoµght to play a role in the regµLation of carcinogenesis. Shi W, et al. J Cell Sci. 2007 Apr 1;120(Pt 7):1216-24 Seong HA, et al. J Biol Chem. 2007 Apr 20;282(16):12272-89 Wordinger RJ, et al. Invest Ophthalmol Vis Sci. 2007 Mar;48(3):1191-200 LeClair RJ, et al. Circ Res. 2007 Mar 30;100(6):826-33 Clonality:Polyclonal Isotype:IgG Purification Method:Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjµgates. Antibodies were purified by affinity-chromatography using epitope-specific peptide. Conjµgate:Non-conjµgated Buffer:Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Form:liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:SMAD3 Research Areas:Epigenetics and Nuclear Signaling;Cancer;Metabolism;Signal transduction?Stem cells