ELISA FH anti-

Quantity :50µL Clone Number: Aliases:FH antibody; Fumarase antibody; Fumarate hydratase antibody; Fumarate hydratase mitochondrial antibody; Fumarate hydratase; mitochondrial antibody; FUMH_ antibody; HLRCC antibody; LRCC antibody; MCL antibody; MCµL 1 antibody; MCµL1 antibody; MS709 antibody; MµLtiple hereditary cutaneous leiomyomata antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:P07954 Immunogen:Fusion protein of FH Raised in:Rabbit Reactivity:, Mouse, Rat Tested Applications:ELISA, WB, IHC; ELISA:1:2000-1:5000, WB:1:500-1:2000, IHC:1:50-1:200 Background:The protein encoded by this gene is an enzymatic component of the tricarboxylic acid (TCA) cycle, or Krebs cycle, and catalyzes the formation of L-malate from fumarate. It exists in both a cytosolic form and an N-terminal extended form, differing only in the translation start site used. The N-terminal extended form is targeted to the mitochondrion, where the removal of the extension generates the same form as in the cytoplasm. It is similar to some thermostable class II fumarases and functions as a homotetramer. Mutations in this gene can cause fumarase deficiency and lead to progressive encephalopathy. Clonality:Polyclonal Isotype:IgG Purification Method:Antigen affinity purification Conjµgate:Non-conjµgated Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:FH Research Areas:Cancer;Metabolism;Signal transduction