ELISA vcp Antibody, Biotin

Quantity :50µL Clone Number: Aliases:vcp antibody; cdc48 antibody; si:ch211-113n10.2Transitional endoplasmic reticµLum ATPase antibody; TER ATPase antibody; EC 3.6.4.6 antibody; Protein CDC48 antibody; Valosin-containing protein antibody; VCP antibody Product Type:Polyclonal Antibody Immunogen Species:Zebrafish UniProt ID:Q7ZU99 Immunogen:Recombinant Zebrafish Transitional endoplasmic reticµLum ATPase protein (704-806AA) Raised in:Rabbit Reactivity:Zebrafish Tested Applications:ELISA Background:Necessary for the fragmentation of Golgi stacks during mitosis and for their reassembly after mitosis. Involved in the formation of the nuclear envelope, and of the transitional endoplasmic reticµLum (tER). The transfer of membranes from the endoplasmic reticµLum to the Golgi apparatus occurs via 50-70 nm transition vesicles which derive from part-roµgh, part-smooth transitional elements of the endoplasmic reticµLum (tER). Vesicle budding from the tER is an ATP-dependent process. Also involved in DNA damage response: recruited to double-strand breaks (DSBs) sites and promotes the recruitment of tp53bp1 at DNA damage sites (By similarity). Enhances cell cycle progression and inhibits apoptosis at low temperatures (PubMed:12914916). Essential for the maturation of ubiquitin-containing autophagosomes and the clearance of ubiquitinated protein by autophagy (By similarity). Acts as a negative regµLator of type I interferon production by promoting ubiquitination of ddx58/rig-i (By similarity). May play a role in the ubiquitin-dependent sorting of membrane proteins to lysosomes where they undergo degradation (By similarity). Clonality:Polyclonal Isotype:IgG Purification Method:>95%, Protein G purified Conjµgate:Biotin Buffer:Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:vcp Research Areas:Neuroscience; Metabolism; Signal transduction