ELISA WDR59 Antibody, Biotin

Quantity :50µL Clone Number: Aliases:WDR59 antibody; KIAA1923 antibody; FP977 antibody; GATOR complex protein WDR59 antibody; WD repeat-containing protein 59 antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:Q6PJI9 Immunogen:Recombinant GATOR complex protein WDR59 protein (619-862AA) Raised in:Rabbit Reactivity: Tested Applications:ELISA Background:As a component of the GATOR subcomplex GATOR2, functions within the amino acid-sensing branch of the TORC1 signaling pathway. Indirectly activates mTORC1 and the TORC1 signaling pathway throµgh the inhibition of the GATOR1 subcomplex (PubMed:23723238). It is negatively regµLated by the upstream amino acid sensors SESN2 and CASTOR1 (PubMed:25457612, PubMed:27487210). Clonality:Polyclonal Isotype:IgG Purification Method:>95%, Protein G purified Conjµgate:Biotin Buffer:Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:WDR59 Research Areas:Cell biology