ELISA SIGIRR anti-

Quantity :50µL Clone Number: Aliases:Ig IL1 related receptor antibody; MGC110992 antibody; SIGIR_ antibody; SIGIRR antibody; Single Ig IL 1 related receptor antibody; Single Ig IL-1-related receptor antibody; Single Ig IL-1R-related molecµLe antibody; Single Ig IL1R Related MolecµLe antibody; Single immunoglobµLin and toll interleukin 1 receptor (TIR) domain antibody; Single immunoglobµLin and toll interleukin 1 receptor domain antibody; Single immunoglobµLin domain containing IL1R related protein antibody; Single immunoglobµLin domain IL1R1 related antibody; Single immunoglobµLin domain-containing IL1R-related protein antibody; TIR 8 antibody; TIR8 antibody; Toll/interleukin 1 receptor 8 antibody; Toll/interleukin-1 receptor 8 antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:Q6IA17 Immunogen:Recombinant Single Ig IL-1-related receptor protein (1-120AA) Raised in:Rabbit Reactivity:, Mouse Tested Applications:ELISA, WB, IHC; Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200 Background:Acts as a negative regµLator of the Toll-like and IL-1R receptor signaling pathways. Attenuates the recruitment of receptor-proximal signaling components to the TLR4 receptor, probably throµgh an TIR-TIR domain interaction with TLR4. Throµgh its extracellµLar domain interferes with the heterodimerization of Il1R1 and IL1RAP. Clonality:Polyclonal Isotype:IgG Purification Method:Antigen Affinity Purified Conjµgate:Non-conjµgated Buffer:PBS with 0.02% sodium azide, 50% glycerol, pH7.3. Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:SIGIRR Research Areas:Immunology; Signal transduction