ELISA PIK3R6 Antibody, Biotin

Quantity :50µg Clone Number: Aliases:C17orf38 antibody; Chromosome 17 open reading frame 38 antibody; HsT41028 antibody; p84 PI3K adapter protein antibody; p84 PIKAP antibody; p87 phosphoinositide 3-kinase gamma (PI3Kg) adapter protein antibody; p87 PI3K adapter protein antibody; p87PIKAP antibody; Phosphatidylinositol 3-kinase; regµLatory subunit 6 antibody; Phosphoinositide 3-kinase gamma adapter protein of 87 kDa antibody; Phosphoinositide 3-kinase regµLatory subunit 6 antibody; PI3Kgamma adapter protein of 87 kDa antibody; PI3R6_ antibody; PIK3R6 antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:Q5UE93 Immunogen:Recombinant Phosphoinositide 3-kinase regµLatory subunit 6 protein (566-667AA) Raised in:Rabbit Reactivity: Tested Applications:ELISA Background:RegµLatory subunit of the PI3K gamma complex. Acts as an adapter to drive activation of PIK3CG by beta-gamma G protein dimers. The PIK3CG:PIK3R6 heterodimer is much less sensitive to beta-gamma G protein dimers than PIK3CG:PIK3R5 and its membrane recruitment and beta-gamma G protein dimer-dependent activation requires HRAS bound to PIK3CG. Recruits of the PI3K gamma complex to a PDE3B:RAPGEF3 signaling complex involved in angiogenesis; signaling seems to involve RRAS. Clonality:Polyclonal Isotype:IgG Purification Method:>95%, Protein G purified Conjµgate:Biotin Buffer:Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:PIK3R6 Research Areas:Signal transduction