ELISA MIA3 anti-

Quantity :50µg Clone Number: Aliases:ARNT antibody; C219 reactive peptide antibody; C219-reactive peptide antibody; D320 antibody; Melanoma inhibitory activity family; member 3 antibody; Melanoma inhibitory activity protein 3 antibody; Mia3 antibody; MIA3_ antibody; RP11-378J18.4 antibody; TANGO antibody; Transport and Golgi organization protein 1 antibody; UNQ6077 antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:Q5JRA6 Immunogen:Recombinant Transport and Golgi organization protein 1 homolog protein (1447-1626AA) Raised in:Rabbit Reactivity: Tested Applications:ELISA Background:Plays a role in the transport of cargos that are too large to fit into COPII-coated vesicles and require specific mechanisms to be incorporated into membrane-bound carriers and exported from the endoplasmic reticµLum. This protein is required for collagen VII (COL7A1) secretion by loading COL7A1 into transport carriers. It may participate in cargo loading of COL7A1 at endoplasmic reticµLum exit sites by binding to COPII coat subunits Sec23/24 and guiding SH3-bound COL7A1 into a growing carrier. Does not play a role in global protein secretion and is apparently specific to COL7A1 cargo loading. However, it may participate in secretion of other proteins in cells that do not secrete COL7A1. It is also specifically required for the secretion of lipoproteins by participating in their export from the endoplasmic reticµLum (PubMed:27138255, PubMed:19269366). Required for correct assembly of COPII coat components at endoplasmic reticµLum exit sites (ERES) and for the localization of SEC16A and membrane-bound ER-resident complexes consisting of CTAGE5 and PREB/SEC12 to ERES (PubMed:28442536). Clonality:Polyclonal Isotype:IgG Purification Method:>95%, Protein G purified Conjµgate:Non-conjµgated Buffer:Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:MIA3 Research Areas:Signal transduction