ELISA PLEKHO1 Antibody, HRP

Quantity :50µg Clone Number: Aliases:C-Jun-binding protein antibody; Casein kinase 2-interacting protein 1 antibody; CK2 interacting protein 1 antibody; CK2 interacting protein 1 HQ0024c protein antibody; CK2-interacting protein 1 antibody; CKIP 1 antibody; CKIP-1 antibody; CKIP1 antibody; JBP antibody; OC120 antibody; Osteoclast maturation associated gene 120 protein antibody; Osteoclast maturation-associated gene 120 protein antibody; PH domain-containing family O member 1 antibody; PKHO1_ antibody; Pleckstrin homology domain containing family O member 1 antibody; Pleckstrin homology domain-containing family O member 1 antibody; PLEKHO1 antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:Q53GL0 Immunogen:Recombinant Pleckstrin homology domain-containing family O member 1 protein (143-404AA) Raised in:Rabbit Reactivity: Tested Applications:ELISA Background:Plays a role in the regµLation of the actin cytoskeleton throµgh its interactions with actin capping protein (CP). May function to target CK2 to the plasma membrane thereby serving as an adapter to facilitate the phosphorylation of CP by protein kinase 2 (CK2). Appears to target ATM to the plasma membrane. Appears to also inhibit tumor cell growth by inhibiting AKT-mediated cell-survival. Also implicated in PI3K-regµLated muscle differentiation, the regµLation of AP-1 activity (plasma membrane bound AP-1 regµLator that translocates to the nucleus) and the promotion of apoptosis induced by tumor necrosis factor TNF. When bound to PKB, it inhibits it probably by decreasing PKB level of phosphorylation. Clonality:Polyclonal Isotype:IgG Purification Method:>95%, Protein G purified Conjµgate:HRP Buffer:Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:PLEKHO1 Research Areas:Signal transduction