ELISA TYROBP anti-
Quantity :50µL
Clone Number:
Aliases:DAP 12 antibody; DAP12 antibody; DNAX activation protein 12 antibody; DNAX-activation protein 12 antibody; KAR-associated protein antibody; KARAP antibody; Killer activating receptor associated protein antibody; Killer-activating receptor-associated protein antibody; PLOSL antibody; TYOBP_ antibody; TYRO protein tyrosine kinase binding protein antibody; TYRO protein tyrosine kinase-binding protein antibody; TYROBP antibody
Product Type:Polyclonal Antibody
Immunogen Species:Homo sapiens ()
UniProt ID:O43914
Immunogen:Synthetic peptide of TYROBP
Raised in:Rabbit
Reactivity:, Mouse, Rat
Tested Applications:ELISA, IHC; ELISA:1:1000-1:10000, IHC:1:25-1:100
Background:This gene encodes a transmembrane signaling polypeptide which contains an immunoreceptor tyrosine-based activation motif (ITAM) in its cytoplasmic domain. The encoded protein may associate with the killer-cell inhibitory receptor (KIR) family of membrane glycoproteins and may act as an activating signal transduction element. This protein may bind zeta-chain (TCR) associated protein kinase 70kDa (ZAP-70) and spleen tyrosine kinase (SYK) and play a role in signal transduction, bone modeling, brain myelination, and inflammation. Mutations within this gene have been associated with polycystic lipomembranous osteodysplasia with sclerosing leukoencephalopathy (PLOSL), also known as Nasu-Hakola disease. Its putative receptor, triggering receptor expressed on myeloid cells 2 (TREM2), also causes PLOSL. MµLtiple alternative transcript variants encoding distinct isoforms have been identified for this gene.
Clonality:Polyclonal
Isotype:IgG
Purification Method:Antigen affinity purification
Conjµgate:Non-conjµgated
Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Form:Liquid
Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names:TYROBP
Research Areas:Signal transduction
Référence interne:
CSB-PA699424
URL de site web:
/shop/csb-pa699424-elisa-tyrobp-anti-180076
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