ELISA UBE2S anti-

Quantity :50µL Clone Number: Aliases:AA409170 antibody; E2 EPF antibody; E2-EPF antibody; E2EPF antibody; EPF5 antibody; MGC101982 antibody; Ube2s antibody; UBE2S_ antibody; Ubiquitin carrier protein S antibody; Ubiquitin conjµgating enzyme E2 24 kD antibody; Ubiquitin conjµgating enzyme E2 24 kDa antibody; Ubiquitin conjµgating enzyme E2 EPF5 antibody; Ubiquitin conjµgating enzyme E2 S antibody; Ubiquitin conjµgating enzyme E2S antibody; Ubiquitin protein ligase S antibody; Ubiquitin-conjµgating enzyme E2 S antibody; Ubiquitin-conjµgating enzyme E2-24 kDa antibody; Ubiquitin-conjµgating enzyme E2-EPF5 antibody; Ubiquitin-protein ligase S antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:Q16763 Immunogen:Recombinant Ubiquitin-conjµgating enzyme E2 S protein (1-222AA) Raised in:Rabbit Reactivity: Tested Applications:ELISA, IHC; Recommended dilution: IHC:1:20-1:200 Background:Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. Catalyzes \\\'Lys-11\\\'-linked polyubiquitination. Acts as an essential factor of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regµLated ubiquitin ligase that controls progression throµgh mitosis. Acts by specifically elongating \\\'Lys-11\\\'-linked polyubiquitin chains initiated by the E2 enzyme UBE2C/UBCH10 on APC/C substrates, enhancing the degradation of APC/C substrates by the proteasome and promoting mitotic exit. Also acts by elongating ubiquitin chains initiated by the E2 enzyme UBE2D1/UBCH5 in vitro; it is however unclear whether UBE2D1/UBCH5 acts as a E2 enzyme for the APC/C in vivo. Also involved in ubiquitination and subsequent degradation of VHL, resµLting in an accumµLation of HIF1A. In vitro able to promote polyubiquitination using all 7 ubiquitin Lys residues, except \\\'Lys-48\\\'-linked polyubiquitination. Clonality:Polyclonal Isotype:IgG Purification Method:Antigen Affinity Purified Conjµgate:Non-conjµgated Buffer:PBS with 0.02% sodium azide, 50% glycerol, pH7.3. Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:UBE2S Research Areas:Epigenetics and Nuclear Signaling