ELISA TRADD anti-

Quantity :50µg Clone Number: Aliases:9130005N23Rik antibody; AA930854 antibody; TNFR1 associated DEATH domain protein antibody; TNFR1-associated DEATH domain protein antibody; TNFRSF1A associated via death domain antibody; TNFRSF1A-associated via death domain antibody; tradd antibody; TRADD_ antibody; Tumor necrosis factor receptor type 1 associated DEATH domain protein antibody; Tumor necrosis factor receptor type 1-associated DEATH domain protein antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:Q15628 Immunogen:Recombinant Tumor necrosis factor receptor type 1-associated DEATH domain protein (1-312AA) Raised in:Rabbit Reactivity:, Rat Tested Applications:ELISA, WB, IHC, IF, IP; Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200, IF:1:50-1:200, IP:1:200-1:2000 Background:The nuclear form acts as a tumor suppressor by preventing ubiquitination and degradation of isoform p19ARF/ARF of CDKN2A by TRIP12: acts by interacting with TRIP12, leading to disrupt interaction between TRIP12 and isoform p19ARF/ARF of CDKN2A (By similarity). Adapter molecµLe for TNFRSF1A/TNFR1 that specifically associates with the cytoplasmic domain of activated TNFRSF1A/TNFR1 mediating its interaction with FADD. Overexpression of TRADD leads to two major TNF-induced responses, apoptosis and activation of NF-kappa-B. Clonality:Polyclonal Isotype:IgG Purification Method:>95%, Protein G purified Conjµgate:Non-conjµgated Buffer:Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:TRADD Research Areas:Cancer; CardiovascµLar; Cell biology