ELISA SQSTM1 Antibody, HRP

Quantity :50µg Clone Number: Aliases:A170 antibody; DMRV antibody; EBI 3 associated protein of 60 kDa antibody; EBI 3 associated protein p60 antibody; EBI3 associated protein of 60 kDa antibody; EBI3 associated protein p60 antibody; EBI3-associated protein of 60 kDa antibody; EBIAP antibody; FTDALS3 antibody; MGC127197 antibody; ORCA antibody; OSF-6 antibody; Osi antibody; OSIL antibody; Oxidative stress induced like antibody; p60 antibody; p62 antibody; p62B antibody; Paget disease of bone 3 antibody; PDB 3 antibody; PDB3 antibody; Phosphotyrosine independent ligand for the Lck SH2 domain of 62 kDa antibody; Phosphotyrosine independent ligand for the Lck SH2 domain p62 antibody; Phosphotyrosine-independent ligand for the Lck SH2 domain of 62 kDa antibody; PKC-zeta-interacting protein antibody; Protein kinase C-zeta-interacting protein antibody; Sequestosome 1 antibody; Sequestosome-1 antibody; SQSTM 1 antibody; SQSTM_ antibody; Sqstm1 antibody; STAP antibody; STONE14 antibody; Ubiquitin binding protein p62 antibody; Ubiquitin-binding protein p62 antibody; ZIP 3 antibody; ZIP antibody; ZIP3 antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:Q13501 Immunogen:Recombinant Sequestosome-1 protein (16-310AA) Raised in:Rabbit Reactivity: Tested Applications:ELISA Background:Autophagy receptor that interacts directly with both the cargo to become degraded and an autophagy modifier of the MAP1 LC3 family. Required both for the formation and autophagic degradation of polyubiquitin-containing bodies, called ALIS (aggresome-like induced structures) and links ALIS to the autophagic machinery. Involved in midbody ring degradation. May regµLate the activation of NFKB1 by TNF-alpha, nerve growth factor (NGF) and interleukin-1. May play a role in titin/TTN downstream signaling in muscle cells. May regµLate signaling cascades throµgh ubiquitination. Adapter that mediates the interaction between TRAF6 and CYLD (By similarity). May be involved in cell differentiation, apoptosis, immune response and regµLation of K(+) channels. Clonality:Polyclonal Isotype:IgG Purification Method:>95%, Protein G purified Conjµgate:HRP Buffer:Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:SQSTM1 Research Areas:Epigenetics and Nuclear Signaling; Cancer; CardiovascµLar; Metabolism; Signal transduction