ELISA TPSB2 anti-
Quantity :50µL
Clone Number:
Aliases:Mast cell tryptase beta II antibody; Mast cell tryptase beta III antibody; TPS2 antibody; TPSB2 antibody; TRYB2_ antibody; Tryptase beta 2 (gene/pseudogene) antibody; Tryptase beta-2 antibody; Tryptase II antibody; Tryptase-2 antibody; TryptaseB antibody; TryptaseC antibody
Product Type:Polyclonal Antibody
Immunogen Species:Homo sapiens ()
UniProt ID:P20231
Immunogen:FµLl length fusion protein
Raised in:Rabbit
Reactivity:
Tested Applications:ELISA, IHC; ELISA:1:2000-1:5000, IHC:1:25-1:100
Background:Tryptases comprise a family of trypsin-like serine proteases, the peptidase family S1. Tryptases are enzymatically active only as heparin-stabilized tetramers, and they are resistant to all known endogenous proteinase inhibitors. Several tryptase genes are clustered on chromosome 16p13.3. These genes are characterized by several distinct features. They have a highly conserved 3' UTR and contain tandem repeat sequences at the 5' flank and 3' UTR which are thoµght to play a role in regµLation of the mRNA stability. These genes have an intron immediately upstream of the initiator Met codon, which separates the site of transcription initiation from protein coding sequence. This feature is characteristic of tryptases but is unusual in other genes. The alleles of this gene exhibit an unusual amount of sequence variation, such that the alleles were once thoµght to represent two separate genes, beta II and beta III. Beta tryptases appear to be the main isoenzymes expressed in mast cells, whereas in basophils, alpha-tryptases predominate. Tryptases have been implicated as mediators in the pathogenesis of asthma and other allergic and inflammatory disorders.
Clonality:Polyclonal
Isotype:IgG
Purification Method:Antigen affinity purification
Conjµgate:Non-conjµgated
Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Form:Liquid
Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names:TPSB2
Research Areas:Others
Référence interne:
CSB-PA608547
URL de site web:
/shop/csb-pa608547-elisa-tpsb2-anti-178022
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