ELISA TRAF3 anti-

Quantity :50µL Clone Number: Aliases:CAP 1 antibody; CAP-1 antibody; CAP1 antibody; CD40 associated protein 1 antibody; CD40 binding protein antibody; CD40 bp antibody; CD40 receptor associated factor 1 antibody; CD40 receptor-associated factor 1 antibody; CD40-binding protein antibody; CD40BP antibody; CRAF 1 antibody; CRAF1 antibody; IIAE5 antibody; LAP 1 antibody; LAP1 antibody; LMP1 associated protein antibody; LMP1-associated protein 1 antibody; MIPT3 antibody; TNF receptor associated factor 3 antibody; TNF receptor-associated factor 3 antibody; TRAF 3 antibody; Traf3 antibody; TRAF3_ antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:Q13114 Immunogen:Synthetic peptide of TRAF3 Raised in:Rabbit Reactivity: Tested Applications:ELISA, WB, IHC; ELISA:1:2000-1:5000, WB:1:200-1:1000, IHC:1:50-1:200 Background:The protein encoded by this gene is a member of the TNF receptor associated factor (TRAF) protein family. TRAF proteins associate with, and mediate the signal transduction from, members of the TNF receptor (TNFR) superfamily. This protein participates in the signal transduction of CD40, a TNFR family member important for the activation of the immune response. This protein is found to be a critical component of the lymphotoxin-beta receptor (LTbetaR) signaling complex, which induces NF-kappaB activation and cell death initiated by LTbeta ligation. Epstein-Barr virus encoded latent infection membrane protein-1 (LMP1) can interact with this and several other members of the TRAF family, which may be essential for the oncogenic effects of LMP1. Several alternatively spliced transcript variants encoding three distinct isoforms have been reported. Clonality:Polyclonal Isotype:IgG Purification Method:Antigen affinity purification Conjµgate:Non-conjµgated Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:TRAF3 Research Areas:Cancer;Immunology;Signal transduction