ELISA TWIST2 anti-

Quantity :100µL Clone Number: Aliases:bHLHa39 antibody; Class A basic helix-loop-helix protein 39 antibody; Dermis expressed protein 1 antibody; Dermis-expressed protein 1 antibody; DERMO 1 antibody; Dermo-1 antibody; DERMO1 antibody; MGC117334 antibody; Twist 2 antibody; Twist homolog 2 (Drosophila) antibody; Twist homolog 2 antibody; Twist related bHLH protein Dermo1 antibody; Twist related protein 2 antibody; Twist-related protein 2 antibody; Twist2 antibody; TWST2_ antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:Q8WVJ9 Immunogen:Peptide sequence around aa.26~30(P-K-R-F-G) derived from Twist2. Raised in:Rabbit Reactivity:, Mouse, Rat Tested Applications:ELISA, WB; WB:1:500-1:1000 Background: Binds to the E-box consensus sequence 5'-CANNTG-3' as a heterodimer and inhibits transcriptional activation by MYOD1, MYOG, MEF2A and MEF2C. Also represses expression of proinflammatory cytokines such as TNFA and IL1B. Involved in postnatal glycogen storage and energy metabolism. Inhibits the premature or ectopic differentiation of preosteoblast cells during osteogenesis, possibly by changing the internal signal transduction response of osteoblasts to external growth factors. Lee M.S., Lowe G., Flanagan S., Kuchler K., Glackin C.A.Bone 27:591-602(2000) Clonality:Polyclonal Isotype:IgG Purification Method:Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjµgates. Antibodies were purified by affinity-chromatography using epitope-specific peptide. Conjµgate:Non-conjµgated Buffer:Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Form:liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:TWIST2 Research Areas:Epigenetics and Nuclear Signaling;Stem cells