ELISA STAT5A anti-

Quantity :50µL Clone Number: Aliases:MGF antibody; Signal transducer and activator of transcription 5A antibody; Signal Transducer and Activator of Transcription 5B antibody; STA5A_ antibody; STAT 5A antibody; STAT 5B antibody; STAT5 antibody; STAT5A antibody; STAT5B antibody; Transcription factor STAT5A antibody; Transcription factor STAT5B antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:P42229 Immunogen:Fusion protein of STAT5A Raised in:Rabbit Reactivity:, Mouse, Rat Tested Applications:ELISA, WB, IHC; ELISA:1:500-1:5000, WB:1:500-1:2000, IHC:1:25-1:100 Background:The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is activated by, and mediates the responses of many cell ligands, such as IL2, IL3, IL7 GM-CSF, erythropoietin, thrombopoietin, and different growth hormones. Activation of this protein in myeloma and lymphoma associated with a TEL/JAK2 gene fusion is independent of cell stimµLus and has been shown to be essential for the tumorigenesis. The mouse counterpart of this gene is found to induce the expression of BCL2L1/BCL-X(L), which sµggests the antiapoptotic function of this gene in cells. Clonality:Polyclonal Isotype:IgG Purification Method:Antigen affinity purification Conjµgate:Non-conjµgated Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:STAT5A Research Areas:Epigenetics and Nuclear Signaling;Signal transduction