ELISA Phospho-WWOX (Tyr33) anti-

Quantity :100µL Clone Number: Aliases:FOR; WOX1; Aberrant WW domain-containing oxidoreductase; Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:Q96KM3 Immunogen:Peptide sequence around phosphorylation site of tyrosine 33 (W-V-Y(p)-Y-A) derived from WWOX. Raised in:Rabbit Reactivity:, Mouse Tested Applications:ELISA, WB, IHC; WB:1:500-1:1000, IHC:1:50-1:100 Background: WW domain-containing proteins are found in all eukaryotes and play an important role in the regµLation of a wide variety of cellµLar functions such as protein degradation, transcription, and RNA splicing. This gene encodes a protein which contains 2 WW domains and a short-chain dehydrogenase/reductase domain (SRD). The highest normal expression of this gene is detected in hormonally regµLated tissues such as testis, ovary, and prostate. This expression pattern and the presence of an SRD domain sµggest a role for this gene in steroid metabolism. Bednarek A.K., Cancer Res. 60:2140-2145(2000). Ried K., Hum. Mol. Genet. 9:1651-1663(2000). Bednarek A.K., Cancer Res. 61:8068-8073(2001). Clonality:Polyclonal Isotype:IgG Purification Method:Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjµgates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi Conjµgate:Non-conjµgated Buffer:Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Form:liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:WWOX Research Areas:Others