ELISA TRAF1 anti-

Quantity :50µL Clone Number: Aliases:4732496E14Rik antibody; EBI6 antibody; EBV induced protein 6 antibody; Epstein-Barr virus-induced protein 6 antibody; MGC:10353 antibody; Tnf receptor associated factor 1 antibody; TNF receptor-associated factor 1 antibody; TRAF 1 antibody; TRAF1 antibody; TRAF1_ antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:Q13077 Immunogen:Fusion protein of TRAF1 Raised in:Rabbit Reactivity:, Mouse Tested Applications:ELISA, WB, IHC; ELISA:1:1000-1:2000, WB:1:200-1:1000, IHC:1:25-1:100 Background:The protein encoded by this gene is a member of the TNF receptor (TNFR) associated factor (TRAF) protein family. TRAF proteins associate with, and mediate the signal transduction from various receptors of the TNFR superfamily. This protein and TRAF2 form a heterodimeric complex, which is required for TNF-alpha-mediated activation of MAPK8/JNK and NF-kappaB. The protein complex formed by this protein and TRAF2 also interacts with inhibitor-of-apoptosis proteins (IAPs), and thus mediates the anti-apoptotic signals from TNF receptors. The expression of this protein can be induced by Epstein-Barr virus (EBV). EBV infection membrane protein 1 (LMP1) is found to interact with this and other TRAF proteins; this interaction is thoµght to link LMP1-mediated B lymphocyte transformation to the signal transduction from TNFR family receptors. Clonality:Polyclonal Isotype:IgG Purification Method:Antigen affinity purification Conjµgate:Non-conjµgated Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:TRAF1 Research Areas:Epigenetics and Nuclear Signaling;Cancer;Cell biology;Microbiology?Signal transduction