ELISA GEMIN2 anti-

Quantity :50µL Clone Number: Aliases:Component of gems 2 antibody; Gem (nuclear organelle) associated protein 2 antibody; Gem associated protein 2 antibody; GEMI2_ antibody; Gemin-2 antibody; gemin2 antibody; SIP 1 antibody; SIP-1 antibody; SIP1 antibody; SIP1 delta antibody; SIP1-delta antibody; SMN interacting protein 1 antibody; SMN interacting protein 1 delta antibody; SMN-interacting protein 1 antibody; Survival interacting protein 1 antibody; Survival of motor neuron protein interacting protein 1 antibody; Survival of motor neuron protein-interacting protein 1 antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:O14893 Immunogen:Synthetic peptide of GEMIN2 Raised in:Rabbit Reactivity:, Mouse, Rat Tested Applications:ELISA, IHC; ELISA:1:1000-1:5000, IHC:1:25-1:100 Background:This gene encodes one of the proteins found in the SMN complex, which consists of several gemin proteins and the protein known as the survival of motor neuron protein. The SMN complex is localized to a subnuclear compartment called gems (gemini of coiled bodies) and is required for assembly of spliceosomal snRNPs and for pre-mRNA splicing. This protein interacts directly with the survival of motor neuron protein and it is required for formation of the SMN complex. A knockout mouse targeting the mouse homolog of this gene exhibited disrupted snRNP assembly and motor neuron degeneration. Clonality:Polyclonal Isotype:IgG Purification Method:Antigen affinity purification Conjµgate:Non-conjµgated Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:GEMIN2 Research Areas:Neuroscience;Signal transduction