ELISA TMEM123 anti-

Quantity :50µL Clone Number: Aliases:TMEM123 antibody; KCT3 antibody; PSEC0111 antibody; UNQ641/PRO1271 antibody; Porimin antibody; Keratinocytes-associated transmembrane protein 3 antibody; KCT-3 antibody; Pro-oncosis receptor inducing membrane injury antibody; Transmembrane protein 123 antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:Q8N131 Immunogen:Fusion protein of TMEM123 Raised in:Rabbit Reactivity: Tested Applications:ELISA, IHC; ELISA:1:2000-1:10000, IHC:1:30-1:150 Background:This gene encodes a highly glycosylated transmembrane protein with a high content of threonine and serine residues in its extracellµLar domain, similar to a broadly defined category of proteins termed mucins. Exposure of some cell types to anti-PORIMIN (pro-oncosis receptor inducing membrane injury) antibody, crosslinks this protein on the cell surface and induces a type of cell death termed oncosis. Oncosis is distinct from apoptosis and is characterized by a loss of cell membrane integrity without DNA fragmentation. This gene product is proposed to function as a cell surface receptor that mediates cell death. Clonality:Polyclonal Isotype:IgG Purification Method:Antigen affinity purification Conjµgate:Non-conjµgated Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:TMEM123 Research Areas:Cancer;Cell biology