ELISA SCN5A anti-

Quantity :100µL Clone Number: Aliases:Cardiac tetrodotoxin insensitive voltage dependent sodium channel alpha subunit antibody; CDCD2 antibody; CMD1E antibody; CMPD2 antibody; HB1 antibody; HB2 antibody; HBBD antibody; HH1 antibody; ICCD antibody; IVF antibody; LQT3 antibody; PFHB1 antibody; Scn5a (gene name) antibody; Scn5a antibody; SCN5A_ antibody; Sodium channel protein cardiac muscle alpha subunit antibody; Sodium channel protein cardiac muscle subunit alpha antibody; Sodium channel protein type 5 subunit alpha antibody; Sodium channel protein type V alpha subunit antibody; Sodium channel protein type V subunit alpha antibody; SSS1 antibody; VF1 antibody; Voltage gated sodium channel alpha subunit Nav1.5 antibody; Voltage-gated sodium channel subunit alpha Nav1.5 antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:Q14524 Immunogen:SyntheQuantityd peptide derived from sodium channel. Raised in:Rabbit Reactivity:, Mouse, Rat Tested Applications:ELISA, WB, IHC; WB:1:500-1:3000, IHC:1:50-1:100 Background:This protein mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel throµgh which Na+ ions may pass in accordance with their electrochemical gradient. It is a tetrodotoxin-resistant Na+ channel isoform. This channel is responsible for the initial upstroke of the action potential. Channel inactivation is regµLated by intracellµLar calcium levels. Sebastian K.G. Maier, CircµLation, Mar 2004; 109: 1421 - 1427. T.R. Cummins, Neurology, Jan 2003; 60: 224 - 229. Christopher A. Ahern, Circ. Res., May 2005; 96: 991 - 998. Jyoti Dhar Malhotra, CircµLation, Mar 2001; 103: 1303 - 1310. Clonality:Polyclonal Isotype:IgG Purification Method:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. Conjµgate:Non-conjµgated Buffer:Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Form:liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:SCN5A Research Areas:Neuroscience;CardiovascµLar