ELISA TPH2 (Ab-19) anti-

Quantity :100µL Clone Number: Aliases:MGC138871 antibody; ADHD7 antibody; FLJ37295 antibody; MGC138872 antibody; Neuronal tryptophan hydroxylase antibody; NTPH antibody; TPH 2 antibody; Tph2 antibody; TPH2_ antibody; Tryptophan 5-hydroxylase 2 antibody; Tryptophan 5-monooxygenase 2 antibody; Tryptophan hydroxylase 2 antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:Q8IWU9 Immunogen:SyntheQuantityd non-phosphopeptide derived from TPH2 around the phosphorylation site of serine 19 (G-FI-S(p)-L-D). Raised in:Rabbit Reactivity:, Mouse Tested Applications:ELISA, WB; WB:1:500-1:3000 Background:This gene encodes a member of the pterin-dependent aromatic acid hydroxylase family. The encoded protein catalyzes the first and rate limiting step in the biosynthesis of serotonin, an important hormone and neurotransmitter. The genome contains two related tryptophan hydroxylases, one on chromosome 11p15-p14 and one on chromosome 12q21. This gene is expressed predominantly in the brain stem. Mutations in this gene may be associated with psychiatric diseases such as bipolar affective disorder and major depression. Bader M., Science 299:76-76(2003). Gibbs R.A., Nature 440:346-351(2006). Pandey A., Proc. Natl. Acad. Sci. U.S.A. 104:2199-2204(2007). Clonality:Polyclonal Isotype:IgG Purification Method:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. Conjµgate:Non-conjµgated Buffer:Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Form:liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:TPH2 Research Areas:Neuroscience