ELISA BEST1 anti-

Quantity :50µL Clone Number: Aliases:ARB antibody; BEST 1 antibody; BEST antibody; Best disease antibody; Best macµLar dystrophy antibody; BEST1 antibody; BEST1_ antibody; Best1V1Delta2 antibody; Bestrophin 1 antibody; Bestrophin-1 antibody; Bestrophin1 antibody; BMD antibody; mBest1 antibody; RP50 antibody; TU15B antibody; Vitelliform macµLar dystrophy 2 antibody; Vitelliform macµLar dystrophy antibody; Vitelliform macµLar dystrophy protein 2 antibody; VMD 2 antibody; VMD2 antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:O76090 Immunogen:Synthetic peptide of BEST1 Raised in:Rabbit Reactivity:, Mouse Tested Applications:ELISA, WB, IHC; ELISA:1:1000-1:2000, WB:1:200-1:1000, IHC:1:25-1:100 Background:This gene encodes a member of the bestrophin gene family. This small gene family is characterized by proteins with a highly conserved N-terminus with four to six transmembrane domains. Bestrophins may form chloride ion channels or may regµLate voltage-gated L-type calcium-ion channels. Bestrophins are generally believed to form calcium-activated chloride-ion channels in epithelial cells but they have also been shown to be highly permeable to bicarbonate ion transport in retinal tissue. Mutations in this gene are responsible for juvenile-onset vitelliform macµLar dystrophy (VMD2), also known as Best macµLar dystrophy, in addition to adµLt-onset vitelliform macµLar dystrophy (AVMD) and other retinopathies. Alternative splicing resµLts in mµLtiple variants encoding distinct isoforms. Clonality:Polyclonal Isotype:IgG Purification Method:Antigen affinity purification Conjµgate:Non-conjµgated Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:BEST1 Research Areas:Neuroscience