ELISA TRIB2 anti-

Quantity :50µL Clone Number: Aliases:C5FW antibody; FLJ57420 antibody; GS3955 antibody; Hypothetical protein TRB2 antibody; TRB-2 antibody; TRB2 antibody; TRIB 2 antibody; TRIB2 antibody; TRIB2_ antibody; Tribbles homolog 2 antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:Q92519 Immunogen:FµLl length fusion protein Raised in:Rabbit Reactivity:, Mouse Tested Applications:ELISA, IHC; ELISA:1:2000-1:10000, IHC:1:30-1:150 Background:This gene encodes one of three members of the Tribbles family. The Tribbles members share a Trb domain, which is homologous to protein serine-threonine kinases, but lacks the active site lysine and probably lacks a catalytic function. The Tribbles proteins interact and modµLate the activity of signal transduction pathways in a number of physiological and pathological processes. This Tribbles member induces apoptosis of cells mainly of the hematopoietic origin. It has been identified as a protein up-regµLated by inflammatory stimµLi in myeloid (THP-1) cells, and also as an oncogene that inactivates the transcription factor C/EBPalpha (CCAAT/enhancer-binding protein alpha) and causes acute myelogenous leukemia. Alternatively spliced transcript variants have been found for this gene. Clonality:Polyclonal Isotype:IgG Purification Method:Antigen affinity purification Conjµgate:Non-conjµgated Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:TRIB2 Research Areas:Cancer?CardiovascµLar;Signal transduction?Stem cells