ELISA CKMT1A anti-

Quantity :50µL Clone Number: Aliases:Acidic-type mitochondrial creatine kinase antibody; CKMT antibody; CKMT1 antibody; CKMT1B antibody; Creatine kinase mitochondrial 1 (ubiquitous) antibody; Creatine kinase mitochondrial 1B antibody; Creatine kinase U type mitochondrial antibody; Creatine kinase U-type antibody; KCRU_ antibody; Mia-CK antibody; mitochondrial antibody; U-MtCK antibody; Ubiquitous mitochondrial creatine kinase antibody; UMTCK antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:P12532 Immunogen:Synthetic peptide of CKMT1A/CKMT1B Raised in:Rabbit Reactivity: Tested Applications:ELISA, IHC; ELISA:1:1000-1:5000, IHC:1:50-1:200 Background:Mitochondrial creatine (MtCK) kinase is responsible for the transfer of high energy phosphate from mitochondria to the cytosolic carrier, creatine. It belongs to the creatine kinase isoenzyme family. It exists as two isoenzymes, sarcomeric MtCK and ubiquitous MtCK, encoded by separate genes. Mitochondrial creatine kinase occurs in two different oligomeric forms: dimers and octamers, in contrast to the exclusively dimeric cytosolic creatine kinase isoenzymes. Many malignant cancers with poor prognosis have shown overexpression of ubiquitous mitochondrial creatine kinase; this may be related to high energy turnover and failure to eliminate cancer cells via apoptosis. Ubiquitous mitochondrial creatine kinase has 80% homology with the coding exons of sarcomeric mitochondrial creatine kinase. Two genes located near each other on chromosome 15 have been identified which encode identical mitochondrial creatine kinase proteins. Clonality:Polyclonal Isotype:IgG Purification Method:Antigen affinity purification Conjµgate:Non-conjµgated Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:CKMT1A Research Areas:Cancer;Cell biology;Metabolism;Signal transduction