ELISA PKD1 anti-

Quantity :50µg Clone Number: Aliases:Autosomal dominant polycystic kidney disease 1 protein antibody; Autosomal dominant polycystic kidney disease protein 1 antibody; nPKC-D1 antibody; nPKC-mu antibody; OTTHUMP00000208669 antibody; OTTHUMP00000208670 antibody; PBP antibody; Pc-1 antibody; PKD antibody; Pkd1 antibody; PKD1_ antibody; Polycystic Kidney Disease 1 antibody; polycystic kidney disease-associated protein antibody; Polycystin 1 Precursor antibody; Polycystin-1 antibody; Protein kinase C mu type antibody; Protein kinase D antibody; Serine/threonine-protein kinase D1 antibody; transient receptor potential cation channel; subfamily P; member 1 antibody; TRPP1 antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:P98161 Immunogen:Recombinant Polycystin-1 protein (615-753AA) Raised in:Rabbit Reactivity: Tested Applications:ELISA, IHC, IF; Recommended dilution: IHC:1:500-1:1000, IF:1:200-1:500 Background:Involved in renal tubµLogenesis (PubMed:12482949). Involved in fluid-flow mechanosensation by the primary cilium in renal epithelium (By similarity). Acts as a regµLator of cilium length, together with PKD2 (By similarity). The dynamic control of cilium length is essential in the regµLation of mechanotransductive signaling (By similarity). The cilium length response creates a negative feedback loop whereby fluid shear-mediated deflection of the primary cilium, which decreases intracellµLar cAMP, leads to cilium shortening and thus decreases flow-induced signaling (By similarity). May be an ion-channel regµLator. Involved in adhesive protein-protein and protein-carbohydrate interactions. Clonality:Polyclonal Isotype:IgG Purification Method:>95%, Protein G purified Conjµgate:Non-conjµgated Buffer:Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:PKD1 Research Areas:Cancer; Metabolism; Signal transduction