ELISA Phospho-PLCG2 (Tyr1217) anti-

Quantity :100µL Clone Number: Aliases:1 phosphatidylinositol 4 5 bisphosphate phosphodiesterase gamma 2 antibody; 1-phosphatidylinositol-4 antibody; 5-bisphosphate phosphodiesterase gamma-2 antibody; EC 3.1.4.11 antibody; Phosphoinositide phospholipase C antibody; Phosphoinositide phospholipase C-gamma-2 antibody; Phospholipase C gamma 2 antibody; Phospholipase C, gamma 2 (phosphatidylinositol specific) antibody; Phospholipase C-gamma-2 antibody; Phospholipase C-IV antibody; PLC 2 antibody; PLC gamma 2 antibody; PLC IV antibody; PLC-gamma-2 antibody; PLC-IV antibody; Plcg2 antibody; PLCG2_ antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:P16885 Immunogen:Peptide sequence around phosphorylation site of tyrosine 1217 (F-L-Y(p)-D-T) derived from PLCg2. Raised in:Rabbit Reactivity:, Mouse, Rat Tested Applications:ELISA, IHC; IHC:1:50-1:100 Background:The production of the second messenger molecµLes diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. It is a crucial enzyme in transmembrane signaling. Yue, C. et al. (1998) J. Biol. Chem. 273, 18023-18027. Yue, C. et al. (2000) J. Biol. Chem. 275, 30220-30225. Margolis, B. et al. (1989) Cell 57, 1101-1107. Clonality:Polyclonal Isotype:IgG Purification Method:Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjµgates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi Conjµgate:Non-conjµgated Buffer:Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Form:liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:PLCG2 Research Areas:Cancer?CardiovascµLar;Metabolism;Signal transduction