ELISA TNIP3 anti-

Quantity :50µL Clone Number: Aliases:TNIP3 antibody; ABIN3 antibody; LIND antibody; TNFAIP3-interacting protein 3 antibody; A20-binding inhibitor of NF-kappa-B activation 3 antibody; ABIN-3 antibody; Listeria-induced gene protein antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:Q96KP6 Immunogen:Synthetic peptide of TNIP3 Raised in:Rabbit Reactivity:, Mouse Tested Applications:ELISA, WB; ELISA:1:1000-1:2000, WB:1:200-1:1000 Background:TNIP3, which called LIND, that was upregµLated in monocytes infected with Listeria monocytogenes. The predicted 325-amino acid protein contains 3 coiled-coil domains and is most likely localized to the nucleus. Binds to zinc finger protein TNFAIP3 and inhibits NF-kappa-B activation induced by tumor necrosis factor, Toll-like receptor 4 (TLR4), interleukin-1 and 12-O-tetradecanoylphorbol-13-acetate. Overexpression inhibits NF-kappa-B-dependent gene expression in response to lipopolysaccharide at a level downstream of TRAF6 and upstream of IKBKB. NF-kappa-B inhibition is independent of TNFAIP3 binding. Clonality:Polyclonal Isotype:IgG Purification Method:Antigen affinity purification Conjµgate:Non-conjµgated Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:TNIP3 Research Areas:CardiovascµLar;Signal transduction