ELISA ACLY anti-

Quantity :50µL Clone Number: Aliases:ACL antibody; Acly antibody; ACLY_ antibody; ATP citrate (pro-S) lyase antibody; ATP citrate lyase antibody; ATP citrate synthase antibody; ATP-citrate (pro-S-)-lyase antibody; ATP-citrate synthase antibody; ATPcitrate synthase antibody; ATPCL antibody; Citrate cleavage enzyme antibody; CLATP antibody; OTTHUMP00000164773 antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:P53396 Immunogen:Fusion protein of ACLY Raised in:Rabbit Reactivity:, Mouse, Rat Tested Applications:ELISA, WB; ELISA:1:2000-1:5000, WB:1:500-1:2000 Background:ATP citrate lyase is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues. The enzyme is a tetramer (relative molecµLar weight approximately 440,000) of apparently identical subunits. It catalyzes the formation of acetyl-CoA and oxaloacetate from citrate and CoA with a concomitant hydrolysis of ATP to ADP and phosphate. The product, acetyl-CoA, serves several important biosynthetic pathways, including lipogenesis and cholesterogenesis. In nervous tissue, ATP citrate-lyase may be involved in the biosynthesis of acetylcholine. Two transcript variants encoding distinct isoforms have been identified for this gene. Clonality:Polyclonal Isotype:IgG Purification Method:Antigen affinity purification Conjµgate:Non-conjµgated Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:ACLY Research Areas:Cancer;Metabolism;Signal transduction