ELISA Phospho-BLM (Thr99) anti-

Quantity :100µL Clone Number: Aliases:Blm antibody; BLM_ antibody; Bloom syndrome antibody; Bloom syndrome protein antibody; Bloom syndrome RecQ helicase like antibody; BS antibody; DNA helicase antibody; DNA helicase RecQ like type 2 antibody; MGC126616 antibody; MGC131618 antibody; MGC131620 antibody; RECQ 2 antibody; RECQ like antibody; RecQ like type 2 antibody; RecQ protein like 3 antibody; RecQ protein-like 3 antibody; RecQ-like type 2 antibody; RecQ2 antibody; RECQL 2 antibody; RECQL 3 antibody; RECQL2 antibody; RECQL3 antibody; type 2 antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:P54132 Immunogen:Peptide sequence around phosphorylation site of threonine 99 (Q-E-T(p)-Q-R) derived from Bloom Syndrome. Raised in:Rabbit Reactivity: Tested Applications:ELISA, WB, IHC; WB:1:500-1:1000, IHC:1:50-1:100 Background: Participates in DNA replication and repair. Exhibits a magnesium-dependent ATP-dependent DNA-helicase activity that unwinds single- and double-stranded DNA in a 3'-5' direction. Involved in 5'-end resection of DNA during double-strand break (DSB) repair: unwinds DNA and recruits DNA2 which mediates the cleavage of 5'-ssDNA. Negatively regµLates sister chromatid exchange (SCE). Ellis N.A., Cell 83:655-666(1995). Karow J.K., J. Biol. Chem. 272:30611-30614(1997). Pichierri P., EMBO J. 23:3154-3163(2004). Clonality:Polyclonal Isotype:IgG Purification Method:Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjµgates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi Conjµgate:Non-conjµgated Buffer:Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Form:liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:BLM Research Areas:Epigenetics and Nuclear Signaling