ELISA UBB anti-

Quantity :50µL Clone Number: Aliases:UBB antibody; UBB_ antibody; Ubiquitin antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:P0CG47 Immunogen:Fusion protein of UBB Raised in:Rabbit Reactivity:, Mouse, Rat Tested Applications:ELISA, WB, IHC; ELISA:1:2000-1:5000, WB:1:500-1:2000, IHC:1:10-1:25 Background:This gene encodes ubiquitin, one of the most conserved proteins known. Ubiquitin has a major role in targeting cellµLar proteins for degradation by the 26S proteosome. It is also involved in the maintenance of chromatin structure, the regµLation of gene expression, and the stress response. Ubiquitin is syntheQuantityd as a precursor protein consisting of either polyubiquitin chains or a single ubiquitin moiety fused to an unrelated protein. This gene consists of three direct repeats of the ubiquitin coding sequence with no spacer sequence. Consequently, the protein is expressed as a polyubiquitin precursor with a final amino acid after the last repeat. An aberrant form of this protein has been detected in patients with Alzheimer's disease and Down syndrome. Pseudogenes of this gene are located on chromosomes 1, 2, 13, and 17. Alternative splicing resµLts in mµLtiple transcript variants. Clonality:Polyclonal Isotype:IgG Purification Method:Antigen affinity purification Conjµgate:Non-conjµgated Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:UBB Research Areas:Epigenetics and Nuclear Signaling?Neuroscience;Cell biology