ELISA DMRT3 anti-

Quantity :50µL Clone Number: Aliases:DMRT3 antibody; DMRTA3Doublesex- and mab-3-related transcription factor 3 antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:Q9NQL9 Immunogen:Fusion protein of DMRT3 Raised in:Rabbit Reactivity:, Mouse, Rat Tested Applications:ELISA, WB, IHC; ELISA:1:2000-1:5000, WB:1:500-1:2000, IHC:1:100-1:300 Background:The DMRT (doublesex and mab-3 related transcription factor) genes encode a large family of transcription factors that are related to the Drosophila doublesex proteins. Expressed primarily in the gonads, DMRT proteins contain cysteine-rich DNA-binding motifs and are thoµght to play an important role in sexual development. DMRT3 (doublesex and mab-3 related transcription factor 3), also known as DMRTA3, is a 472 amino acid protein that contains one DM DNA-binding domain and belongs to the DMRT family. Localized to the nucleus, DMRT3 is expressed specifically in testis and is thoµght to regµLate transcriptional events during early sexual development. The gene encoding DMRT3 maps to chromosome 9, which houses over 900 genes and comprises nearly 4% of the genome. Hereditary hemorrhagic telangiectasia, which is characterized by harmfµL vascµLar defects, and Familial dysautonomia, are both associated with chromosome 9. Notably, chromosome 9 encompasses the largest interferon family gene cluster. Clonality:Polyclonal Isotype:IgG Purification Method:Antigen affinity purification Conjµgate:Non-conjµgated Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:DMRT3 Research Areas:Cancer;Developmental biology;Metabolism